Skaare, Dagfinn; Anthonisen, Inger Lill; Caugant, Dominique A; Jenkins, Andrew; Steinbakk, Martin; Strand, Linda; Sundsfjord, Arnfinn; Tveten, Yngvar; Kristiansen, Bjørn-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Background
Beta-lactam resistance in Haemophilus influenzae due to ftsI mutations causing altered penicillin-binding protein 3 (PBP3) is increasing worldwide. Low-level resistant isolates with the N526K substitution (group II low-rPBP3) predominate in most geographical regions, while high-level resistant isolates with the additional S385T substitution (group III high-rPBP3) are common in Japan ...